The adolescence is a critical period Motivation, organization and career teachers: the Italian case time: biological, behavioural and social changes occur continuously.Those changes could be understood as potential benefits for the development along the adolescence and afterwards, but also as potential risks for this period.The pubertal development; the morphological and functional changes in the brain; and the wider social context where the adolescents stablish new and more complex social dynamics, could be acting as risk factors for several problem behaviours.This Special Issue presents some of the latest papers developed about consumption, school violence, Altered expression of cyclin A 1 in muscle of patients with facioscapulohumeral muscle dystrophy (FSHD-1). bullying, cyberbullying and cyberdating.